Myostatin , also known as GDF-8, a conserved member of the TGF-β superfamily, is an essential regulator of skeletal muscle mass and cardiac muscle development and function. Myostatin is a secreted protein that negatively regulates skeletal muscle growth by determining muscle fiber number and size. Myostatin binds one of the two activin type II receptors (ACTRIIA, ACTRIIB) to activate SMAD signaling. Myostatin also activates MAPK signaling through TAK1-MKK6 and Ras pathways. Inhibition of myostatin increases muscle mass in a number of human disease animal models, such as muscular dystrophy.
- Product Name: GDF-8 (Myostatin) 1mg
- Catalogue Number: GDF8-1mg
- Purity: ≥95%
- Form: Lyophilised Solid
Usage and Storage:
GDF-8 (Myostatin) is supplied as a lyophilised solid to ensure maximum stability and ease of use in research environments. For best results, follow our website’s detailed reconstitution and storage guidelines.
Production and Quality Assurance:
GDF-8 (Myostatin) is meticulously produced through a controlled recombinant expression process that guarantees high purity (≥95%) and biological activity, making it suitable for precise scientific studies. Our commitment to excellence ensures that each batch undergoes stringent quality control to meet the rigorous standards researchers require.
Legal and Safety Information:
UK-Peptides proudly provides GDF-8 (Myostatin) strictly for scientific and research use. In alignment with our dedication to supporting the research community, we ensure our products meet stringent quality standards and legal requirements. Please note that our proteins, including GDF-8 (Myostatin), are not designed for human consumption or clinical application.
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Key Features:
- Purity: >99% (HPLC tested)
- Form: Lyophilized powder
- Quantity: 1mg
- Research Use Only: Not for human consumption
Mechanism of Action:
GDF-8 inhibitors work by binding to and neutralizing myostatin, effectively removing the natural “brake” on muscle growth. This results in enhanced muscle hypertrophy and strength in test subjects, making it a focus of studies in muscle wasting diseases, age-related muscle loss, and athletic performance enhancement.
Potential Research Applications:
- Muscle hypertrophy and strength enhancement
- Sarcopenia and cachexia models
- Regenerative medicine
- Muscular dystrophy research
- Metabolic and obesity-related studies
Storage Instructions:
Store lyophilized peptide at -20°C. Once reconstituted with bacteriostatic water, store in a refrigerator (2–8°C) and use within 14 days for optimal stability.
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Frequently Asked Questions (FAQ)
GDF-8 (Myostatin Inhibitor) 1mg
1. What is GDF-8 (Myostatin Inhibitor)?
GDF-8, also known as Myostatin, is a protein that regulates and limits muscle growth. This product is a Myostatin Inhibitor, meaning it blocks the effects of GDF-8, potentially allowing for increased muscle development in research models.
2. What is this product used for?
GDF-8 (Myostatin Inhibitor) is intended for research purposes only. It is commonly used in studies related to:
- Muscle growth and hypertrophy
- Muscle wasting diseases (e.g., sarcopenia, cachexia)
- Regenerative therapies
- Metabolic and obesity-related conditions
3. Is this product safe for human use?
No. This peptide is strictly intended for laboratory research only and is not approved for human consumption. It should only be handled by qualified professionals in a controlled research setting.
4. How should GDF-8 be stored?
- Lyophilized (powder) form: Store at -20°C in a dry, dark place.
- After reconstitution: Store at 2–8°C and use within 14 days for best stability.
Avoid repeated freeze-thaw cycles.
5. How is GDF-8 typically reconstituted?
The peptide can be reconstituted using bacteriostatic water or sterile saline, depending on lab protocols. Ensure the solution is prepared under sterile conditions to maintain peptide integrity.
6. What is the purity level of this peptide?
This GDF-8 Myostatin Inhibitor is >99% pure, verified by HPLC (High Performance Liquid Chromatography) testing to ensure consistent quality and research reliability.
7. How is the peptide packaged and shipped?
Each vial contains 1mg of lyophilized peptide and is vacuum-sealed to preserve stability. Products are shipped with insulation and cold packs when required to ensure they remain viable during transit.
8. Can I use this in combination with other peptides or compounds?
While some researchers do explore stacking peptides, any combination should be thoroughly reviewed and aligned with your specific research goals. Always follow ethical research guidelines and consult relevant literature.
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Vendor: PeptideNationUSA
Brandon Keller –
I’ve been stacking GDF-8 with my usual peptides and saw a noticeable increase in muscle fullness and reduced fat retention. Definitely worth it
Lisa Monroe –
I was skeptical at first, but the strength gains were real within a few weeks. Great quality product!
Anthony Salazar –
Recovery time between intense sessions has dropped significantly. Felt more pumped and less sore.
Rachel Kim –
Great for advanced lifters trying to break plateaus. No side effects so far. Will order again.
Derek Waller –
Highly recommend for serious athletes. The lean gains have been impressive and sustained.